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HomeRequisitions and Provider ToolsNon-invasive Prenatal Testing (NIPT) Requisitions
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Non-invasive Prenatal Testing (NIPT) Requisitions

OHIP-Funded NIPT

    Dynacare | Harmony Prenatal Test

      Download Requisition  

      Download MOH Checklist  

    LifeLabs | Panorama NIPT

     Download Requisition and MOH Checklist 

     

    All twin pregnancies are now eligible for OHIP-funded NIPT

    • Dynacare: The MOH Checklist has been updated to reflect this change.
    • LifeLabs: The MOH Checklist (page 2 of the requisition) is in the process of being updated to reflect the change in OHIP-funding criteria for twin pregnancies. Until the update is completed, we encourage you to write out "twin pregnancy" under "Indication Category 1" to order OHIP-funded NIPT for your patient.

    Provincial NIPT Labs at a Glance

    Factors to consider when choosing between the two provincial NIPT labs:

     Singletons
     
    Pregnancy TypeQuestions to ConsiderHarmony® Prenatal Test | DynacarePanoramaTM NIPT |
    LifeLabs

    non-IVF singleton pregnancy

    Can NIPT be done?

    Yes

    Yes

    IVF singleton pregnancy

    Can NIPT be done when a pregnant individual's own oocytes are used? 

    Yes

    Yes

    IVF singleton pregnancy

    Can NIPT be done when a gestational carrier (surrogate) is involved?

    Yes

    Yes

    IVF singleton pregnancy

    Can NIPT be done when donor eggs (not self) are used?

    Yes

    Yes

    Any singleton pregnancy

    Can NIPT screen for sex chromosome aneuploidies?1

    Yes, and is optional (opt-in for monosomy X, sex chromosome aneuploidies)

    Yes, and is not optional (screening for sex chromosome aneuploidies is part of standard testing - cannot opt out)

    Any singleton pregnancy  Can NIPT be done in a "vanishing" twin / co-twin demise scenario?2  No  No

     

    1 - Twin pregnancies generally cannot be screened for sex chromosome aneuploidies.  However, PanoramaTM can screen for sex chromosome aneuploidies in monozygotic twin pregnancies only. 

    2 - "Vanishing" twin pregnancy is a pregnancy that started as a twin pregnancy with subsequent loss of fetal heart activity or loss of the embryo in one of the pregnancy sacs. 

     Multiple Gestation (twins or more)
    For most twin pregnancies, NIPT can be ordered through either LifeLabs or Dynacare. There are two types of IVF twin pregnancies that can only have NIPT through Dynacare: donor egg was used or a surrogate is involved.
    Pregnancy TypeQuestions to ConsiderHarmony® Prenatal Test | Dynacare                                      PanoramaTM NIPT | LifeLabs
    non-IVF twin pregnancy Can NIPT be done?

    Yes

    • Yes
    • Zygosity testing is included (which means it can can tell you if the twins are identical or fraternal)1

    IVF twin pregnancy

    Can NIPT be done when a pregnant individual's own oocytes are used? 

    Yes

    • Yes
    • Zygosity testing is included 

    IVF twin pregnancy

    Can NIPT be done when a gestational carrier (surrogate) is involved?

    Yes

    No (only singletons)

    IVF twin pregnancy

    Can NIPT be done when donor eggs (not self) are used?

    Yes

    No (only singletons)

    Any pregnancy Can NIPT be done for higher order multiples? No No

     1 -  Chorionicity, rather than zygosity, has an impact on the outcome of twin pregnancies. Zygosity testing can complement, but not replace, ultrasound evaluation of chorionicity in some clinical scenarios. For example, evaluating zygosity through NIPT may impact pregnancy surveillance when chronicity assignment is uncertain, and can help interpret “high risk” aneuploidy results. 

    Private-Pay NIPT

    If none of the MOH criteria for OHIP-funded NIPT are met, a pregnant individual may choose to pay for private-pay NIPT, meaning that they can pay for this testing themselves or may get it covered through private health insurance.

    Private-pay NIPT can be ordered through LifeLabs and Dynacare, as well as other commercial laboratories. Please note that different requisitions are needed for private-pay NIPT than for OHIP-funded NIPT, and these requisitions can be found on the labs' websites.

    Prenatal Screening Ontario is unable to endorse any specific private-pay test or laboratory. On our website, we encourage you to read further about what factors you and the pregnant individual in your care may choose to consider when making decisions about private-pay tests.


    Are you a health-care provider who would like to schedule a virtual education session about prenatal screening in Ontario?  

    Contact Us 


     

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      • Multiple Marker Screening (MMS) Requisitions
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